A complete schedule and scoreboard for football’s top-10 teams during week seven of the 2021 season is below.
CLASS 5A
| 1 | Valor Christian | 7-0 |
| Friday: W 47-14 at Castle View | ||
| 2 | Cherry Creek | 6-1 |
| Friday: W 21-13 vs. No. 4 Grandview | ||
| 3 | Ralston Valley | 6-1 |
| Thursday: L 3-17 vs. Pomona | ||
| 4 | Grandview | 5-2 |
| Friday: L 13-21 at No. 2 Cherry Creek | ||
| 5 | Regis Jesuit | 4-3 |
| Saturday: L 41-42 at No. 6 Legend | ||
| 6 | Legend | 6-1 |
| Saturday: vs. W 42-41 No. 5 Regis Jesuit | ||
| 7 | Columbine | 5-2 |
| Thursday: W 56-13 vs. Lakewood | ||
| 8 | Arvada West | 6-1 |
| Friday: W 35-14 at Mullen | ||
| 9 | Arapahoe | 6-1 |
| Thursday: W 42-28 at Cherokee Trail | ||
| 10 | Douglas County | 6-1 |
| Saturday: L 7-35 at No. 3 Pine Creek (4A) | ||
CLASS 4A
| 1 | Montrose | 7-0 |
| Friday: W 56-12 vs. Heritage | ||
| 2 | Dakota Ridge | 7-0 |
| Friday: W 59-18 at Standley Lake | ||
| 3 | Pine Creek | 6-1 |
| Saturday: W 35-7 vs. No. 10 Douglas County (5A) | ||
| 4 | Erie | 7-0 |
| Friday: W 47-27 at Brighton | ||
| 5 | Palmer Ridge | 6-1 |
| Friday: W 35-28 at No. 8 Ponderosa | ||
| 6 | Loveland | 6-1 |
| Saturday: W 48-0 at Skyline | ||
| 7 | Chatfield | 5-2 |
| Thursday: L 10-14 vs. Bear Creek | ||
| 8 | Ponderosa | 5-2 |
| Friday: L 28-35 vs. No. 5 Palmer Ridge | ||
| 9 | Golden | 7-0 |
| Friday: W 42-0 at Wheat Ridge | ||
| 10 | Fountain-Fort Carson | 6-1 |
| Friday: W 42-28 vs. Fruita Monument | ||
CLASS 3A
| 1 | Roosevelt | 6-0 |
| Friday: W 37-7 vs. No. 2 Mead | ||
| 2 | Mead | 4-1 |
| Friday: L 7-37 at No. 1 Roosevelt | ||
| 3 | Lutheran | 6-0 |
| Friday: W 46-2 at No. 7 Evergreen | ||
| 4 | Fort Morgan | 5-0 |
| Thursday: W 52-27 at Niwot | ||
| 5 | Frederick | 5-0 |
| Friday: W 55-22 at Skyview | ||
| 6 | Durango | 4-2 |
| Friday: W 42-0 vs. Harrison | ||
| 7 | Evergreen | 5-1 |
| Friday: L 2-46 vs. No. 3 Lutheran | ||
| 8 | Holy Family | 4-2 |
| Friday: W 20-7 at Thompson Valley | ||
| 9 | Palisade | 4-2 |
| Friday: W 28-17 at Battle Mountain | ||
| 10 | Pueblo South | 3-2 |
| Off Week | ||
CLASS 2A
| 1 | Eaton | 6-0 |
| Saturday: W 10-6 vs. No. 2 Resurrection Christian | ||
| 2 | Resurrection Christian | 4-1 |
| Saturday: L 6-10 at No. 1 Eaton | ||
| 3 | The Classical Academy | 5-0 |
| Friday: W 70-13 at Lamar | ||
| 4 | Moffat County | 6-0 |
| Friday: W 46-13 at Rifle | ||
| 5 | Severance | 6-0 |
| Friday: W 40-0 at Berthoud | ||
| 6 | Delta | 5-1 |
| Friday: W 56-0 at Aspen | ||
| 7 | Basalt | 5-1 |
| Friday: W 48-12 at Coal Ridge | ||
| 8 | The Academy | 4-2 |
| Friday: L 28-41 vs. University | ||
| 9 | Brush | 4-2 |
| Friday: W 61-16 vs. Valley | ||
| 10 | Elizabeth | 5-2 |
| Friday: W 54-0 vs. Alameda | ||
CLASS 1A
| 1 | Limon | 6-0 |
| Saturday: W 49-7 vs. Burlington | ||
| 2 | Centauri | 5-0 |
| Off Week | ||
| 3 | Florence | 7-0 |
| Friday: W 48-0 at Grand Valley | ||
| 4 | Buena Vista | 7-0 |
| Friday: W 49-6 vs. Rye | ||
| 5 | Wray | 5-1 |
| Friday: W 28-11 at No. 6 Holyoke | ||
| 6 | Holyoke | 4-2 |
| Friday: L 11-28 vs. No. 5 Wray | ||
| 7 | North Fork | 4-2 |
| Friday: L 13-30 at Meeker | ||
| 8 | Wiggins | 5-1 |
| Friday: W 30-28 vs. No. 10 Yuma | ||
| 9 | Strasburg | 4-3 |
| Saturday: W 67-0 at Prospect Ridge | ||
| 10 | Yuma | 3-3 |
| Friday: L 28-30 at No. 8 Wiggins | ||
8-MAN
| 1 | Mancos | 5-0 |
| Off Week | ||
| 2 | Haxtun | 7-0 |
| Friday W 36-12 at No. 3 Sedgwick County | ||
| 3 | Sedgwick County | 3-2 |
| Friday: L 12-36 vs. No. 2 Haxtun | ||
| 4 | Dayspring Christian | 5-2 |
| Saturday: W 56-20 vs. Denver Christian | ||
| 5 | Sanford | 4-1 |
| Off Week | ||
| 6 | Vail Christian | 6-0 |
| Friday: W 44-0 at Hayden | ||
| 7 | Akron | 4-2 |
| Friday: W 46-34 at No. 9 Merino | ||
| 8 | Dove Creek | 4-2 |
| Friday: W over Soroco (Forfeit) | ||
| 9 | Merino | 2-4 |
| Friday: L 34-46 vs. No. 7 Akron | ||
| 10 | Holly | 5-1 |
| Friday: W 66-30 at Las Animas | ||
6-MAN
| 1 | Cheyenne Wells | 6-0 |
| Friday: W 45-6 at No. 10 Cheraw | ||
| 2 | Stratton | 5-1 |
| Friday: W 65-0 at Flagler | ||
| 3 | Fleming | 6-1 |
| Friday: W 54-21 vs. Briggsdale | ||
| 4 | Granada | 5-1 |
| Friday: W over Walsh (Forfeit) | ||
| 5 | Prairie | 5-2 |
| Thursday: L 42-47 at No. 7 Idalia | ||
| 6 | Branson/Kim | 6-0 |
| Saturday: W 70-0 at Miami-Yoder | ||
| 7 | Idalia | 4-2 |
| Thursday: W 47-42 vs. No. 5 Prairie | ||
| 8 | Sierra Grande | 5-0 |
| Saturday: at Cripple Creek-Victor (Canceled) | ||
| 9 | Genoa-Hugo | 5-0 |
| Off Week | ||
| 10 | Cheraw | 4-3 |
| Friday: L 6-45 vs. No. 1 Cheyenne Wells | ||