A complete schedule and scoreboard for football’s top-10 teams during Week 10 of the 2022 season is below.
CLASS 5A
| 1 | Cherry Creek | 8-2 |
| Friday: L 21-24 vs. No. 6 Grandview | ||
| 2 | Valor Christian | 8-2 |
| Friday: W 49-35 at Mountain Vista | ||
| 3 | Ralston Valley | 8-2 |
| Friday: W 49-21 vs. Arvada West | ||
| 4 | Columbine | 9-1 |
| Friday: W 56-0 at Chatfield | ||
| 5 | Regis Jesuit | 6-3 |
| Saturday: vs. Fountain-Fort Carson | ||
| 6 | Grandview | 8-2 |
| Friday: W 24-21 at No. 1 Cherry Creek | ||
| 7 | ThunderRidge | 9-1 |
| Friday: W 13-10 at Rock Canyon | ||
| 8 | Pine Creek | 7-2 |
| Saturday: vs. Chaparral | ||
| 9 | Legacy | 8-2 |
| Friday: W 42-14 at Brighton | ||
| 10 | Fairview | 9-1 |
| Thursday: W 24-7 at Rocky Mountain | ||
CLASS 4A
| 1 | Palmer Ridge | 10-0 |
| Friday: W 24-17 at No. 8 Vista Ridge | ||
| 2 | Broomfield | 10-0 |
| Friday: W 17-13 at No. 7 Heritage | ||
| 3 | Loveland | 9-1 |
| Thursday: W 47-0 at Longmont | ||
| 4 | Denver South | 9-1 |
| Friday: W 49-20 vs. Thomas Jefferson | ||
| 5 | Montrose | 8-2 |
| Friday: W 35-28 vs. Pueblo West | ||
| 6 | Ponderosa | 8-2 |
| Thursday: W 49-7 vs. Bear Creek | ||
| 7 | Heritage | 7-3 |
| Friday: L 13-17 vs. No. 2 Broomfield | ||
| 8 | Vista Ridge | 7-3 |
| Friday: L 17-24 vs. No. 1 Palmer Ridge | ||
| 9 | Fruita Monument | 6-3 |
| Saturday: at Adams City | ||
| 10 | Erie | 6-4 |
| Thursday: W 44-6 vs. Greeley West | ||
CLASS 3A
| 1 | Roosevelt | 9-0 |
| Friday: W 42-12 at Thompson Valley | ||
| 2 | Durango | 7-1 |
| Saturday: vs. Palisade | ||
| 3 | Green Mountain | 9-0 |
| Friday: W 65-0 vs. Littleton | ||
| 4 | Lutheran | 7-2 |
| Friday: W 55-14 vs. Kennedy | ||
| 5 | Northridge | 7-1 |
| Saturday: at No. 6 Resurrection Christian | ||
| 6 | Resurrection Christian | 7-1 |
| Saturday: vs. No. 5 Northridge | ||
| 7 | Holy Family | 5-3 |
| Saturday: at Lincoln | ||
| 8 | Evergreen | 7-2 |
| Friday: W 70-7 at Wheat Ridge | ||
| 9 | Summit | 8-1 |
| W vs. Battle Mountain (Forfeit) | ||
| 10 | Pueblo East | 7-2 |
| Thursday: L 13-16 at Discovery Canyon | ||
CLASS 2A
| 1 | The Classical Academy | 8-1 |
| Friday: L 14-15 at No. 7 Elizabeth | ||
| 2 | Delta | 9-0 |
| Friday: W 42-0 vs. Montezuma-Cortez | ||
| 3 | Eaton | 8-1 |
| Thursday: W 25-13 at No. 5 The Academy | ||
| 4 | Basalt | 9-0 |
| Thursday: W 49-14 at Aspen | ||
| 5 | The Academy | 7-2 |
| Thursday: L 13-25 vs. No. 3 Eaton | ||
| 6 | Florence | 7-1 |
| Saturday: at La Junta | ||
| 7 | Elizabeth | 7-2 |
| Friday: W 15-14 vs. No. 1 Classical Academy | ||
| 8 | Moffat County | 7-2 |
| Thursday: W 41-0 at Grand Valley | ||
| 9 | Alamosa | 6-3 |
| Friday: W14-0 at Woodland Park | ||
| 10 | D’Evelyn | 7-2 |
| Friday: W 33-0 at Valley | ||
CLASS 1A
| 1 | Limon | 9-0 |
| Friday: W 28-0 vs. No. 7 Yuma | ||
| 2 | Wray | 6-3 |
| Friday: L 14-28 at No. 8 Wiggins | ||
| 3 | Strasburg | 8-1 |
| Friday: W 54-0 vs. Platte Canyon | ||
| 4 | Monte Vista | 8-1 |
| Friday: L 24-28 vs. No. 6 Centauri | ||
| 5 | Buena Vista | 6-2 |
| Friday: at Cedaredge | ||
| 6 | Centauri | 7-2 |
| Friday: W 28-24 at No. 4 Monte Vista | ||
| 7 | Yuma | 6-3 |
| Friday: L 0-28 at No. 1 Limon | ||
| 8 | Wiggins | 6-3 |
| Friday: W 28-14 vs. No. 2 Wray | ||
| 9 | Gunnison | 6-3 |
| Bye Week | ||
| 10 | Rye | 8-1 |
| Friday: W (Forfeit) vs. Rocky Ford | ||
8-MAN
| 1 | Haxtun | 9-0 |
| Friday: W 54-22 at Merino | ||
| 2 | Dove Creek | 9-0 |
| Friday: W 50-12 at Sargent | ||
| 3 | Simla | 9-0 |
| Friday: W 59-0 vs. St. Mary’s | ||
| 4 | Mancos | 7-2 |
| Bye Week | ||
| 5 | Lyons | 9-0 |
| Thursday: W 58-18 vs. Belleview Christian | ||
| 6 | Crowley County | 9-0 |
| Friday: W 76-24 at John Mall | ||
| 7 | Akron | 6-2 |
| Saturday: at Caliche | ||
| 8 | Holly | 7-2 |
| Friday: L 28-30 at Swink | ||
| 9 | Vail Christian | 6-1 |
| Friday: vs. Rangely | ||
| 10 | Sanford | 6-3 |
| Friday: W 44-14 vs. Dolores | ||
6-MAN
| 1 | Stratton | 10-0 |
| Friday: W 53-13 at No. 2 Fleming | ||
| 2 | Fleming | 7-2 |
| Friday: L 13-53 vs. No. 1 Stratton | ||
| 3 | Arickaree | 7-2 |
| Bye Week | ||
| 4 | Cheyenne Wells | 5-3 |
| Saturday: at No. 10 Branson/Kim | ||
| 5 | Granada | 5-3 |
| PPD: at Sierra Grande | ||
| 6 | Otis | 7-2 |
| Bye Week | ||
| 7 | Genoa-Hugo | 7-2 |
| Friday: W 56-7 vs. Hanover | ||
| 8 | North Park | 6-2 |
| Saturday: vs. Mountain Valley | ||
| 9 | Eads | 6-3 |
| Friday: W 84-28 at Idalia | ||
| 10 | Branson/Kim | 7-2 |
| Saturday: vs. No. 4 Cheyenne Wells | ||